Natural cannabinoids are derived directly from hemp or cannabis, while synthetics are manufactured or modified in the laboratory. These distinctions concern their origin, composition and effects on the body. Understanding the differences between natural and synthetic cannabinoids is essential to choosing the right solutions.
The origin and composition of cannabinoids: nature vs. the laboratory
Natural cannabinoids
Natural cannabinoids are organic compounds found in the cannabis plant (Cannabis sativa and Cannabis indica). They are produced in the trichomes, small resin glands found on the flowers.
Cannabinoids come in a wide variety, with around 200 listed in each species. The best-known cannabinoids are of course THC (tetrahydrocannabinol) and CBD (cannabidiol). But we're also hearing more and more about CBN (cannabinol) and CBG (cannabigerol), the precursors of other cannabinoids.
Each molecule has its own specific features and effects, whether sedative, psychoactive, anti-inflammatory or anxiolytic. Their main asset is their synergistic interaction, also known as the entourage effect. This connection between the various cannabinoids and the body amplifies their benefits. Their concentration can vary according to variety and growing conditions.
Synthetic cannabinoids
Synthetic cannabinoids, on the other hand, are created in laboratories. They mimic or modify the natural effects of the cannabinoids present in cannabis. Their molecular structure is designed to target the receptors of the endocannabinoid system with greater intensity. These include medical substances such as Dronabinol and Nabilone, as well as more or less controversial recreational compounds such as spice HHC (Hexahydrocannabinol) and H4CBD, a hydrogenated version of CBD.
There may be cannabinoids that are entirely synthetically engineered in the laboratory, or semi-synthetic molecules that feature a modification on the chain of atoms starting from a natural cannabinoid base, such as CBD and THC. While synthetics enable precise dosing, they can present risks of side effects, as they are much more powerful.
The effects of natural and synthetic cannabinoids on the body
Natural cannabinoids work in harmony with the body's own endocannabinoid system. They regulate essential functions such as pain, appetite and mood. They offer balanced effects thanks to the entourage effect, where several compounds interact to amplify their benefits.
On the other hand, synthetic cannabinoids, designed to mimic or amplify these effects, often bind more strongly to receptors in the brain, leading to much more intense and unpredictable responses. While some are used medicinally, others are available over the counter in certain countries or on the web.
They can have side effects such as anxiety, hallucinations, intense euphoria and memory problems. In comparison, natural cannabinoids will be better tolerated, but their effects depend more on dosage and quality.
Using synthetic cannabinoids properly
To use synthetic cannabinoids responsibly, we advise you to follow certain guidelines.
First of all, you need to know where the product comes from, and choose reputable stores that guarantee the quality and traceability of their products. Synthetic cannabinoids, such as HHC or H4CBD, should be purchased from reliable sources, to reduce the risks introduced by poor-quality products.
You'll also need to consult consumer reviews to assess the customer experience, and this helps to make the use of these products safer. Always start with low doses to see how your body reacts, and avoid mixing cannabinoids.
Finally, comply with current legislation and consult a healthcare professional if you have any doubts about their use.
Whether you're curious about natural or synthetic cannabinoids, it's important to choose quality products to enjoy their benefits safely. Why not take a look our website ? You'll find a rigorous selection, practical advice and everything you need to know to enjoy the benefits of cannabinoids.